CHRONOLOGICAL EVOLUTION IN THE DEVELOPMENT OF ANTICANCER DRUGS: A COMPREHENSIVE REVIEW
Authors: Dr. R Ashok Kumar, Nerella Indira Rani, N Rojaramani, Dr. S Hemalatha, A V Vasanthi
DOI: 10.37326/ajsev8.12/2067
Page No: 90-101
Abstract
The development of anti-cancer drugs has undergone a significant transformation over the past century, reflecting advances in scientific understanding, technology, and clinical practice. This paper traces the chronological evolution of cancer therapeutics, beginning with the discovery of cytotoxic chemotherapy in the mid-20th century, followed by the introduction of hormone therapies and the rise of combination chemotherapy regimens. In recent decades, breakthroughs in immunotherapy, personalized medicine, and nanotechnology have further revolutionized treatment approaches. This evolving landscape highlights a shift from broad-spectrum cytotoxic agents to more precise, individualized strategies aimed at maximizing efficacy and minimizing toxicity. Understanding this historical progression provides critical context for current innovations and future directions in oncology drug development.
